FEBS JOURNAL《欧洲生物化学学会联合会杂志》(可官网投稿)

FEBS JOURNAL《欧洲生物化学学会联合会杂志》(半月刊). The FEBS Journal is an international peer-reviewed Journal devoted to publication of high-quality papers reporting significant advances in the molecular life sciences. Acceptance decisions are based on the originality and quality of the research and its prospective interest to a wide readership. Papers submitted to The FEBS Journal should provide novel perspectives on a biologically relevant problem and be of interest to a broad readership.

杂志简称:febs j
中文译名:《欧洲生物化学学会联合会杂志》
收录属性:scie(2024版), 目次收录(维普),英文期刊,
自引率:2.80%
投稿方向:生物学、biochemistry & molecular biology 生化与分子生物学

FEBS JOURNAL《欧洲生物化学学会联合会杂志》

SCI/E期刊基本信息

出版周期:半月刊 地区:英国
中科院分区:3区
是否TOP:非TOP期刊
是否综述:非综述期刊
是否OA:非OA期刊
国际标准刊号:ISSN1742-464X/EISSN1432-1033
杂志语言:英语
出版国家:英国

杂志官网 联系方式

出版地址:WILEY-BLACKWELL PUBLISHING,INC,COMMERCE PLACE,350 MAIN ST,MALDEN,USA,MA,02148
杂志邮箱:
投稿网址:https://mc.manuscriptcentral.com/febsj
杂志官方网址:https://febs.onlinelibrary.wiley.com/journal/17424658
出版商网址:http://www.wiley.com/WileyCDA/

杂志投稿要求

投稿须知【杂志社官方网站信息】

Author Guidelines

Aims and Scope

The FEBS Journal is an international peer-reviewed journal devoted to publication of high-quality papers reporting significant advances in the molecular life sciences. Acceptance decisions are based on the originality and quality of the research and its prospective interest to a wide readership. Papers submitted to The FEBS Journal should provide novel perspectives on a biologically relevant problem and be of interest to a broad readership.

The scope of the journal is broad and inclusive. We are particularly interested in papers in which state-of-the-art approaches are applied to bring novel insight into molecular and cellular mechanisms that underlie the functions of molecules, cells and organisms. The journal also welcomes manuscripts of an interdisciplinary nature, including systems approaches that address fundamental concepts in molecular, cellular or organismal biology. The areas of interest of The FEBS Journal include, but are not limited to: Biochemistry; Bioinformatics and Computational Biology; Developmental Biology; Enzymology and Chemical Biology; Evolutionary Biology; Genomics; Immunology; Molecular and Cell Biology; Molecular Mechanisms in Health and Disease; Molecular Microbiology; Molecular Neurobiology; Pathogens and Infection; Proteomics; Signal Transduction; Stem Cells; Structural Biology; Systems Biology and Synthetic Biology

The journal does not accept papers that lack biological insight. Papers describing bioinformatic analysis, modelling or structural studies of specific systems or molecules should include experimental data.

The FEBS Journal also publishes Reviews, Minireviews, Viewpoints and Snapshots on a wide range of topics. These pieces are specially commissioned by our Editorial team and are selected on the basis of their interest to a wide readership. In addition, the journal publishes Special Issues that provide detailed insight into a specific scientific field.

Editorial Board

Information about the journal's Editorial Board is available here: https://febs.onlinelibrary.wiley.com/hub/journal/17424658/editorial-board/editorial-board.

Why Publish in The FEBS Journal?

Why publish in The FEBS Journal? Read about the key features of the journal here: https://febs.onlinelibrary.wiley.com/hub/journal/17424658/why-publish-in-the-febs-journal.

Contact Us

Contact information for the journal’s editorial office and production office is here: https://febs.onlinelibrary.wiley.com/hub/journal/17424658/journal-menu/contact-us.

Editorial Policies

Ethical Standards

Any breach of research or publication ethics including plagiarism, submission of fraudulent results/data including doctored figures, dual publication and false or incomplete attribution of authorship will not be tolerated. It will also be considered malpractice for an author to make inappropriate contact with a referee/Editor during the review process with the aim of influencing the outcome. The FEBS Journal will take action where misconduct is suspected, along the lines of the general principles outlined in Guidelines on Good Publication Practice, produced by the Committee on Publication Ethics (COPE). The Guidelines are available from the COPE website.

Conflicts of Interest

All authors are requested to disclose any actual or potential conflict of interest including any financial, personal or other relationships with other people or organizations within three years of beginning the submitted work that could inappropriately influence, or be perceived to influence, their work.

Authorship

Authors are required to meet the criteria for authorship as recommended by the International Committee of Medical Journal Editors (ICMJE). The specific contributions of each author must be described in an Author Contribution statement.

Requests to add or remove an author, or to rearrange the author names, must be sent to the Editorial Office and must include: (a) the reason the name should be added or removed, or the author names rearranged and (b) written confirmation (e-mail, fax, letter) from all authors that they agree with the addition, removal or rearrangement. In the case of addition or removal of authors, this includes confirmation from the author being added or removed. Any requests to add, delete, or rearrange author names in an already published article will follow the same policies as noted above and result in a corrigendum.

Work involving human or animal subjects or tissues

The FEBS Journal endorses the updated ARRIVE 2.0 Guidelines for reporting in vivo animal experiments. Authors are expected to, at a minimum, include the Essential 10 set of items that are explained and elaborated with examples here and at the ARRIVE Guidelines website. We encourage authors to also include the Recommended Set of items to support best reporting practice, which promotes reproducibility of animal-based research.

Authors should include in the Materials and Methods (Experimental Procedures) section:

A statement identifying the institutional and/or licensing committee approving the experiments, including any relevant details. Care and use of experimental animals must comply with all relevant local animal welfare laws, guidelines and policies. For research reporting experiments on live vertebrates and/or higher invertebrates, experiments must comply with relevant institutional and national guidelines and regulations.

A full description of the anaesthetic and surgical procedures used, and of peri-operative care.

Evidence that authors took adequate steps to ensure that animals did not suffer unnecessarily at any stage of an experiment, whether acute or chronic.

Research involving human subjects should comply with the Code of Ethics of the World Medical Association (Declaration of Helsinki; http://www.cirp.org/library/ethics/helsinki/). If human subjects are used, manuscripts must be accompanied by a statement in the Methods section, indicating that:

The experiments were undertaken with the understanding and written consent of each subject.

The study methodologies conformed to the standards set by the Declaration of Helsinki.

The study methodologies were approved by the local ethics committee.

Authors should ensure that all risks are minimised and the subjects are not injured and do not feel they have been abused as a result of participating in the study. Fully informed consent should always be sought.

In cases of experiments involving minors, in addition to meeting above mentioned precautions, evidence must be presented that the experiments were performed with the understanding and consent of the legal guardian.

The Editor reserves the right to reject a paper if there is doubt as to whether appropriate procedures have been used.

Preprints and Data Availability

Preprints

The FEBS Journal supports rapid and open scientific communication. Authors are free to upload their work to their personal website, their company’s/institution’s repository or archive, or a not-for-profit subject-based preprint server or repository ahead of or concurrently with submission to the journal. Posting a manuscript to a recognised preprint server does not constitute prior publication.

Data Accessibility

The FEBS Journal expects that data supporting the results in the paper will be archived in an appropriate public repository, where available. Authors of Original Articles are required to provide a statement of Data Availability that briefly describes the availability of the supporting data, whether contained in the manuscript (as Supplementary Information), deposited elsewhere, or any exceptions or limitations to the sharing of data or materials. Large-scale or structured datasets must be deposited in appropriate public databases and a link to the repository and the persistent identifier of the dataset (e.g. DOI or accession number) should be included in the Data Availability statement. Whenever possible, the scripts and other artefacts used to generate the analyses presented in the paper should also be publicly archived. Authors are not expected to share data that is sensitive in nature or should not be made publicly available due to privacy, security, and/or safety concerns, such as human subject data or the location of endangered species. See See https://febs.onlinelibrary.wiley.com/hub/data-policy for standard templates to follow when compiling your Data Availability statement (Table 1) and for details of suitable repositories for structured datasets (Table 2).

In addition, throughout the text, accession numbers for data stored in external databases will be hyperlinked to provide access to these data if provided in the following format: Database: XXXX. For example, for the entry 1BEN in the Protein Data Bank, use “PDB: 1BEN”

Structural Data

Authors of manuscripts describing macromolecular structures must deposit the atomic coordinates and related experimental data (structure factor amplitudes/intensities and/or NMR restraints and chemical shifts) in the RCSB Protein Data Bank. If the coordinates have not been released by the PDB, please submit the PDB Summary Validation Report that includes a PDB ID (provided after annotation by the wwPDB) for review at the time of submission. If requested by the Editor and/or referees, the authors must make the atomic coordinates and related experimental data (structure factor amplitudes/intensities and/or NMR restraints and chemical shifts) available for review purposes only.

Enzyme Activity Data

For papers reporting kinetic and thermodynamic data concerning biological catalysts (enzymes, other catalytic proteins and nucleic acids), authors must include the identity of the catalyst, its origin (e.g. species, tissue) and the nature of any post-translational modification. The method of preparation and criteria of purity, assay conditions, methodology, activity and any other information relevant to judging the reproducibility of the results must also be reported. For enzymes, please use the Recommended Name and the Enzyme Commission (EC) number (as defined by the International Union of Biochemistry and Molecular Biology (IUBMB)) upon first mention in the main text and Abstract. Authors are advised to consult the Beilstein Institut STRENDA Commission website for more details and suggestions.

Transparent peer review

The FEBS Journal is participating in a pilot on peer review transparency and you have the choice to opt-out during the submission process. By submitting to this journal, you agree that the reviewer reports, their responses, and the editor’s decision letter will be linked from the published article to where they appear on Publons in the case that the article is accepted. Reviewers can choose to remain anonymous unless they would like to sign their report.

Types of Manuscripts

Original Articles

Original articles are the main form of publication of new research results in The FEBS Journal. There is no formal limitation on length, but an original articles rarely exceeds about 7,500 words (39,000 characters, without spaces). Shorter papers are, of course, welcome and the Editors will make recommendations for shortening any paper if that appears appropriate without loss of essential content. A concise, well-written paper is easier for the Editor and referees to evaluate, which can help to speed up publication.

We have no formal limit on the number of references, again subject to readability, and strongly encourage citation of primary literature, where appropriate, instead of reviews in research articles. It is important to ensure the original authors are given due credit.

Reviews

The FEBS Journal publishes reviews in all areas of the molecular life sciences. Reviews should appeal to a broad readership, including non-specialists. Ideally, reviews should convey new ideas, rather than simply a collation of information on a topic.

Reviews are commissioned by the Editorial team and are subject to peer review; therefore, an invitation to contribute a review does not guarantee acceptance. Authors are encouraged to provide the details of three preferred referees at submission.

To maximise their exposure, all reviews and minireviews are made freely available immediately on publication in The FEBS Journal. Authors of reviews and coordinators of minireviews are also encouraged to record a podcast to accompany their article.

Unsolicited reviews are not considered but, if authors wish to submit a review proposal, they may do so. Pre-submission enquiries about timely contributions can be addressed to Professor Seamus Martin (Editor-in-Chief; martin@febs.org), and should include a 250-word summary, an overview of the article structure, and a list of key recent references.

Minireviews

Please see key points for authors of reviews above, but note the following specific guidance:

Main text: this should normally be 3,000–5,000 words.

References: 50–75 references. If appropriate, please include the other minireviews in the series. The series coordinator will be able to provide authors’ names and titles, and the publisher will insert pagination at proof stage.

Figures and tables: up to 5 figures and tables can be included.

State-of-the-Art Reviews

A State-of-the-Art Review is an invited contribution wherein authors summarise the current state of play in their research area and highlight where the major unresolved questions lie.

Discovery-in-Context Reviews

A Discovery-in-Context Review is an invited contribution that aims to convey the context in which a major scientific advance was made.

Structural Snapshots

A Structural Snapshot is an invited contribution that presents a succinct discussion of a particular structure recently published by the authors’ laboratory.

Viewpoints

A Viewpoint is an invited contribution that aims to convey new ideas or controversial perspectives on cutting-edge topics.

A Guide to…

‘A Guide to…’ review articles are invited contributions that should serve as resources for scientists in complex or fast-moving fields. They should bring clarity to fields where the terminology is complex and evolving, or where there are multiple methodologies used to explore a pathway or process.

Emerging Methods and Technologies

An Emerging Methods and Technologies review is an invited contribution in which an author presents an overview and discusses a recently emerged method that significantly advances and improves cellular and molecular science research, and outlines where its ideal applications lie.

Commentaries

A Commentary is an invited contribution that discusses and contextualises recently published research.

Preparing your Manuscript

Format of initial submission

Initial submissions to The FEBS Journal may be made in any format, including as a single file. All manuscripts must contain the essential elements needed to convey your manuscript, for example Title, Author names and affiliations, Abstract, Keywords, Introduction, Materials and Methods, Results, Conclusions, Figures and Tables with Captions.

Title Page

Title. This should be concise but informative. See http://olabout.wiley.com/WileyCDA/Section/id-828012.html for suggestions on how to optimise your title and abstract for search engine discoverability. Avoid abbreviations.

Authors' names. These should appear below the title, with the first or middle name of each author given in full. Given names should appear first.

Addresses. The laboratories where the work was carried out should be given below the authors' names. If the work was carried out at more than one laboratory, the names of the authors should be followed by superscript numbers, which should also precede the names of the appropriate laboratories.

Corresponding author(s). The full name and address of the author for correspondence, including telephone number and email address, should be given. The author should indicate if any of these should not be published. Authors are encouraged to provide the URL of their departmental website for publication.

Running title. This should contain no more than 50 characters (including spaces).

Abbreviations. These should be defined unless included in the table of accepted abbreviations. They should be introduced only if essential owing to frequent repetition or excessive length of the full name. For further details, see the Nomenclature, symbols, units and abbreviations section below.

Keywords. Please provide up to 5 keywords for original articles and up to 10 for Reviews. These keywords will be printed alongside the abstract and are indexed by PubMed.

Conflicts of Interest. Any real or perceived conflicts must be disclosed on the title page.

Abstract

The abstract should give a concise statement of the problem, the experimental approach, and the major findings and conclusions. The abstract should be carefully worded to reflect search terms on PubMed. It should not contain more than 250 words and should be intelligible without reference to other parts of the paper. References, if cited, should be given in full (without the title of the paper). Abbreviations should be avoided.

Introduction

The Introduction should provide the necessary context to support the importance of the discovery being reported. A brief summary of the major findings should be provided at the end of the Introduction.

Results

The Results section should describe the experiments performed and results obtained therein. The Results should be subdivided with topical subheadings.

Discussion

The Discussion can be subdivided with topical subheadings. It is permissible to combine Results and Discussion if a clearer, shorter paper is produced.

Methods

It is essential to provide sufficient detail in this section to allow others to reproduce the work. There is no word limit and authors are strongly encouraged to report their experimental approaches in detail.

Author Contributions

A short description of the contribution of each author (initials only) should be provided in this section. Authors are required to meet the criteria for authorship as recommended by the International Committee of Medical Journal Editors (ICMJE). Specific categories of contribution include: planned experiments; performed experiments; analysed data; contributed reagents or other essential material; wrote the paper; other.

Acknowledgements

Authors must ensure that they include all funding grant numbers in the Acknowledgments section of the manuscript.

Funding sources and disclosure of conflicts of interest

Authors must identify sources of financial support for the conduct of the research and/or preparation of the article and briefly describe the role of the sponsor(s), if any, in study design; in the collection, analysis and interpretation of data; in the writing of the report; and in the decision to submit the article for publication. If the funding source(s) had no such involvement then this should be stated.

References

The FEBS Journal uses a numbered system for references. References must be cited in the text, starting in the Introduction, by numbers in square brackets, e.g. [1], in numerical order of their citation in the text. In the reference list, titles must be provided for all serial publications.

Reference to articles cited as 'in press' should include the title and the name of the journal. Reference to unpublished work, including papers in preparation, should be kept to a minimum and should be mentioned in parentheses in the text as unpublished work, not in the reference list. The names of all contributors to the work should be given. Personal communications should be mentioned only in the text. Permission must be sought and obtained from the relevant person.

The reference list should appear in numerical order. Examples of the correct styles are shown below:

1. Tsubokawa M, Tohyama Y, Tohyama K, Asahi M, Inazu T, Nakamura H, Saito H & Yamamura H (1997) Interleukin-3

activates Syk in a human myeloblastic leukemia cell line, AML193. Eur J Biochem 249, 792-796.

2. Tsubokawa M, Tohyama Y, Tohyama K, Asahi M, Inazu T, Nakamura H, Saito H & Yamamura H (2002) Interleukin-3 activates Syk in a human myeloblastic leukemia cell line, AML193. Eur J Biochem 269, in press.

3. Tsubokawa M, Tohyama Y, Tohyama K, Asahi M, Inazu T, Nakamura H, Saito H & Yamamura H (2002) Interleukin-3 activates Syk in a human myeloblastic leukemia cell line, AML193. Eur J Biochem 269, doi: 10.1046/j.1432-1033.2002.02960.x

4. Sambrook J, Fritsch EF & Maniatis T (1989) Molecular Cloning: A Laboratory Manual, 2nd edn. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.

5. Langer T & Neupert W (1994) Chaperoning mitochondrial biogenesis. In The Biology of Heat Shock Proteins and Molecular Chaperones (Morimoto RI, Tissières A & Georgopoulos C, eds), pp. 53-83. Cold Spring Harbor Laboratory Press, Plainview, NY.

6. Smith A (2000) The role of potassium channels in lymphocytes. PhD Thesis, University of Bristol, UK.

7. Rep M, van Dijl JM, Suda K, Schatz G, Grivell LA & Suzuki CK (1996) Promotion of mitochondrial membrane complex assembly by a proteolytically inactive yeast Lon. Science 274, 103–106 (erratum appears in Science 275, 741).

8. Tsubokawa M III, Tohyama Y Jr, Tohyama K, Asahi M, Inazu T, Nakamura H, Saito H & Yamamura H (1997) Interleukin-3 activates Syk in a human myeloblastic leukemia cell line, AML193. Eur J Biochem 249, doi: 10.1046/j.1432-1033.2002.02960.x

9. Yous S, Depreux P, Adam G, Caignard DH, Lesieur D, Guardiola B & Renard P (1993) European Patent Application No. EP0562956.

The use of a tool such as EndNote is recommended for reference management and formatting. The EndNote reference style for The FEBS Journal can be found here.

Tables

These must be supplied as editable text and not as embedded figures/objects. They should have a bold title and appear in the text following the references. Experimental conditions and general remarks should appear in a legend between the title and the table. They should not reproduce the detail given in Materials and Methods. Footnotes should be used only if information cannot be included in the legend; they should be indicated by superscript lower-case letters. All columns should have a heading; units should appear under the column heading(s).

Schema

Schema should appear in the text following the references.

Figure legends

Figure legends should appear in the text document following the references, each with a title, and be comprehensible without reference to the text. The figure title must be relevant to the entire figure. Supplementary figure legends should be included in the actual supplementary figure files.

If applicable, error bars should be defined as s.d. or s.e.m. and a precise n value given. Where statistical tests have been used to calculate significance (or lack thereof) the p value should be defined and the name of the statistical test provided in the relevant legend.

Figures

Images should not be modified to change their appearance or enhance any specific feature. Any adjustments of brightness and contrast or colour balance must be applied to the entire image and should not result in loss or gain of information. Unacceptable modifications include the addition, alteration or removal of a particular feature of an image, and splicing of multiple images to suggest that they represent a single field in a micrograph or gel. All figures in manuscripts will be examined for any indication of improper modification, duplication or any other alteration that could affect interpretation of the data. The final acceptance of all manuscripts is contingent upon any concerns relating to the composition of figures being fully resolved.

Molecular mass markers should be included alongside blots, and scale bars must be included in micrographs.

Authors should have their original figures available for review by the Editor or referees, if requested.

Colour figures are published free of charge in the journal. Authors are strongly encouraged to include colour in all figures, including histograms, line graphs, schematics as well as photomicrographs, in order to enhance the quality of data presentation for our readers. In the interest of readers with colour blindness, red-green and blue-yellow colour combinations should be avoided.

Reproduction of a previously published figure should be acknowledged at the end of the figure legend as follows: 'Figure reproduced from [ref. number]'. References to the source should be included in the reference list.

For each reproduced figure, it is the authors’ responsibility to check with the relevant publisher whether permission for reproduction is required. Authors should inform the Editorial Office (febsj@febs.org) when permission is required for a figure. Permission must be obtained before publication and emailed to the Editorial Office.

Supporting Information

All necessary experimental evidence must be included in the main text of their paper so that it is complete and self-contained. Supplementary data is limited to:

movies

3D structures/images [these may be included in the main text, if desired]

large datasets

lists of primers, plasmids and strains

'raw' data (e.g. kinetic stopped flow transients; tables of kinetic data; mass spectrometry mzdata; outputs and analyses from complex data fitting routines, or similar types of output)

Any supporting information that conforms to the above criteria must be included with the original submission and will be subject to peer review. After acceptance, supporting information will be published online exactly as submitted by the authors (i.e. it will not be copyedited and will not be available for checking and editing at proof stage).

All supporting information should be cited within the main text. Additionally, the full titles of all supporting information must be listed in a 'Supporting Information' section after the references. This will provide readers with a 'table of contents' of the supporting information accompanying your published article.

All supporting information (excluding movies) must be included within a single PDF. The full titles and, where appropriate, legends of supplementary data, movies, text, figures and tables should be included above or below each respective supplementary file.

Electronic Artwork

Low-quality images are generally acceptable for review purposes. However, for online and print-on-demand publication, high-quality images are required to prevent the final product being blurred or pixelated. Information on the appropriate file formats for electronic graphics is available here.

To facilitate production of publication-quality artwork, we recommend that authors generate their artwork in software packages incorporating the ability to ‘Save as…’ or ‘Export…’ as TIFF/EPS files, e.g. Adobe Illustrator 7.0 and above (EPS), Adobe Illustrator 9.0 (EPS but can also export files as TIFF), Deneba Canvas 6.0 and above (EPS), CorelDRAW 7.0 and above (EPS), Adobe Photoshop 4.0 and above (TIFF). Authors can export low-resolution figs (GIF/JPG) from these packages for review purposes. EPS files can be produced from other applications (e.g. PowerPoint) BUT results can be unpredictable (e.g. fonts and shading not converted correctly, lines missing, dotted lines becoming solid). All scanned images embedded into other applications should be scanned at the recommended resolutions (see below).

Sizing guidelines

Supply figures at final size widths: 80 mm (single column); 165 mm (double column) or 105 mm (intermediate). Maximum depth is 230 mm. Larger figures will be reduced as appropriate, so please ensure that any line widths and lettering are in proportion to the size of the figure. Figures saved as .tiff, or containing embedded .tiffs, will not be enlarged, as this leads to loss of resolution.

Use sans serif, true-type fonts for labels if possible (preferably Arial or Helvetica), and Times (New) Roman if serif fonts required. Use Courier or Courier New for sequence data.

Line drawing lettering/lines must be clear. The axes of each graph should be lettered with the numerical scale and the measured quantity with units.

Halftones (photographs) must have scale bars where applicable.

Multipart figures should be supplied in the final layout in one file, with each part labelled.

File format and resolution guidelines

Submit TIFF, EPS or PDF files only.

Save line art such as charts, graphs and illustrations in EPS or PDF format. Most programs have a ‘Save as…’ or ‘Export…’ feature to allow you to do this.

Save photographic images in TIFF format. These should be saved at final publication size and should have a resolution of at least 300 dpi (dots per inch) at final size.

Save figures containing a combination of photographic images and text (e.g. annotated photographic images with text labels) as EPS or PDF. Any photographic images embedded within these should be at least 300 dpi.

EPS files should be saved with fonts embedded (and with a TIFF preview if possible).

When creating PDF files, it is essential that Press Quality settings (with a resolution of 300 dpi) are used in your PDF-generating software.

For scanned images, the scanning resolution (at final image size, see above for a guide to sizes) should be 300 dpi to ensure adequate reproduction.

TIFF files can be very large; use LZW compression if possible, as this can greatly reduce the file size. For all TIFF files, it is important not to exceed the resolutions stated. Doing so will not improve the quality of output of your figure, but may produce impractically large files.

Perform a visual check of the quality of the generated image. You should be able to zoom in to about 300% without the image becoming noticeably blurred or pixelated. If the image does appear pixelated at this zoom, go back to the original image and check that it complies with the recommended format and settings.

Colour Modes

Black and white images should be supplied as 'grayscale'.

Colour images should be supplied as RGB.

Graphical Abstracts

The journal publishes graphical abstracts in its online table of contents and content alert emails. This is an opportunity to create not just a concise text summary but also a clear visual representation of your article's main message to attract potential readers (remember: 'a picture is worth a thousand words'). Ideally, graphical abstract files should be colour images containing one or two graphical elements and should be visually attractive and contain minimal text. The main objective of a graphical abstract file is to capture the main message or topic of your paper, at a glance, drawing the reader towards the article. For examples, see a sample issue at: https://febs.onlinelibrary.wiley.com/toc/17424658/283/1

Please provide as two separate Supporting Documents:

A short abstract of up to 70 words as a Word document named 'GraphicalAbstract-text.doc', which is easy to understand by a general readership.

An image file as a TIFF or PDF named 'GraphicalAbstract-figure'. This should be a colour image that simply and clearly emphasises the main finding(s) of your article. Please make sure the image (1) is square, measuring 5.5 inches x 5.5 inches (140 mm x 140 mm), and has a resolution of 300 dpi; (2) does not include too much text and that any labels are clear and simple; (3) uses Arial font 12 to 16 (so that text is easy to read, especially on mobile devices); (4) consists of a single panel of elements that progress clearly from top to bottom, or left to right (to aid understanding).

Cover Illustrations

Authors with a colour figure appearing in an accepted paper that they believe would make a good image for the journal cover are invited to submit a copy of the figure, 21 cm (width) by 16 cm (height), in colour, without any labels or scale bars. Please supply an electronic copy of the figure, with a short legend (max. 15 words), following instructions in the Preparation of electronic artwork for publication section.

Nomenclature, abbreviations, units and symbols

The FEBS Journal prefers abbreviations and nomenclature to follow internationally agreed recommendations, e.g. those of the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology (see https://www.qmul.ac.uk/sbcs/iubmb/). However:

Authors may use commonly used abbreviations/acronyms but these must be defined in the text at first citation and included in the Abbreviations list.

SI units and quantities should be used (see https://www.bipm.org/en/measurement-units/) but Å, cal, p.p.m. can be used where appropriate.

It is often convenient, especially in figures and table headings, to give a multiple of the quantity set or measured by multiplying it by a stated factor. The units in which it is expressed should not be multiplied by a number but may be indicated by prefixes such as: M, k, m, µ, n or p.

A negative index style is used for units.

Square brackets are commonly used to indicate concentrations.

Math formulae

Authors should not use Microsoft Word 2007 equation tool to supply equations/schema. Instead, authors should use the Mathtype plug-in, an equation editor for Word that is freely available to download.

Article Preparation Support

Wiley Editing Services offers expert help with English Language Editing, as well as translation, manuscript formatting, figure illustration, figure formatting, and graphical abstract design – so you can submit your manuscript with confidence.

Also, check out our resources for Preparing Your Article for general guidance about writing and preparing your manuscript.

Online Submission

Online submission of manuscripts is via https://mc.manuscriptcentral.com/febsj/. Step-by-step instructions on how to submit your manuscript are available online during the submission process, which does not need to be completed in one session. Any queries can be sent to the Editorial Office (febsj@febs.org).

New submissions

Submitted manuscripts are assigned to a handling Editor who is responsible for its evaluation. The Editor-in-Chief's decision regarding publication is based on the reports of referees and the handling Editor's recommendation, which will, at the Editor-in-Chief's discretion, be transmitted to the authors. Authors will be informed of the editorial decision, on average, within a month of submission of an Original Article. The status of your manuscript can be checked via your ‘Author Centre’ at: https://mc.manuscriptcentral.com/febsj/. Enquiries should be addressed to the Editorial Office (febsj@febs.org).

This journal works together with FEBS Open Bio to enable rapid publication of good-quality research that cannot be accepted for publication by The FEBS Journal. Authors may be offered the option of transferring the paper, along with any related peer reviews, to FEBS Open Bio for consideration by its Editors.

At initial submission, we recommend that authors submit their text, figures and tables as a single PDF file. Alternatively, the following files will be automatically converted into a single PDF:

The manuscript (including title page, abstract, main text, references and tables) saved as a PDF, .doc or .rtf file. Tables should be included after the references.

Figures can either be included in the main text file for reviewing purposes, or be provided as separate files (see Preparation of electronic artwork for publication for details of recommended file formats). All figures must be given a figure number.

Supplementary material (e.g. large datasets or raw data supporting an existing figure; see Supporting Information).

NB Any unpublished papers that are cited must be uploaded as Supporting Documents for referees to access. An electronic copy of any related paper under consideration or in press elsewhere must also be submitted as a Supporting Document; failure to do so may delay the review process.

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